PLoS ONE (Jan 2022)

A 15-year follow-up study of hip bone mineral density and associations with leisure time physical activity. The Tromsø Study 2001-2016.

  • Saija Mikkilä,
  • Jonas Johansson,
  • Anna Nordström,
  • Peter Nordström,
  • Nina Emaus,
  • Bjørn Helge Handegård,
  • Bente Morseth,
  • Boye Welde

DOI
https://doi.org/10.1371/journal.pone.0262228
Journal volume & issue
Vol. 17, no. 1
p. e0262228

Abstract

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AimsThe aim was to investigate the long-term association between leisure time physical activity and hip areal bone mineral density (aBMD), in addition to change in hip aBMD over time, in 32-86 years old women and men.MethodsData were retrieved from the 2001, 2007-2008, and 2015-2016 surveys of the Tromsø Study, a longitudinal population study in Norway. Leisure time physical activity was assessed by the four-level Saltin-Grimby Physical Activity Level Scale which refers to physical exertion in the past twelve months. Hip aBMD was assessed by Dual-Energy X-ray Absorptiometry. Linear Mixed Model analysis was used to examine long-term associations between physical activity and hip aBMD (n = 6324). In addition, the annual change in hip aBMD was analyzed in a subsample of 3199 participants.ResultsPhysical activity was significantly and positively associated with total hip aBMD in the overall cohort (pConclusionsIn this cohort of adult men and women, physical activity levels were positively associated with hip aBMD in a dose-response relationship. Hip aBMD decreased with age, although more pronounced in women than men.