Green and Cost-Effective Synthesis of Sulfamidophosphonates Using ZnO Nanoparticles as Catalyst

Abstract

A simple and efficient protocol for the one-pot three-component synthesis of structurally diverse sulfamidophosphonates from the condensation of sulfanilamide, aldehydes, and triethylphosphite in ethanol using ZnO nanoparticles as catalysts under microwave irradiation has been developed. The structures of all compounds have been identified by appropriate spectroscopic methods such as FTIR, 1H, 13C, 31P NMR and ESI-MS.

Keywords

• sulfamidophosphonate
• microwave
• ZnO nanoparticles
• catalyst