Diabetes, Metabolic Syndrome and Obesity (Sep 2021)
Use of Anthropometric Measures of Obesity to Predict Diabetic Retinopathy in Patients with Type 2 Diabetes in China
Abstract
Qiu-Xue Yi,1 Li-Na Zhu,1 Jing Ma,2 Xin-Jie Yu,1 Lin Liu,1 Jie Shen1 1Department of Ophthalmology, Renji Hospital Affiliated with Shanghai Jiao Tong University School of Medicine, Shanghai, 200127, People’s Republic of China; 2Department of Endocrinology, Renji Hospital Affiliated with Shanghai Jiao Tong University School of Medicine, Shanghai, 200127, People’s Republic of ChinaCorrespondence: Lin Liu; Jie ShenDepartment of Ophthalmology, Renji Hospital Affiliated with Shanghai Jiao Tong University School of Medicine, No. 160 Pujian Road, Pudong New District, Shanghai, 200127, People’s Republic of ChinaEmail [email protected]; [email protected]: Obesity is an established risk factor for type 2 diabetes (T2D). Diabetic retinopathy (DR) is a major microvascular complication of T2D. In this cross-sectional study, we investigated the association between various anthropometric indices of obesity and DR.Patients and Methods: A representative sample of 1952 patients with T2D participated in this cross-sectional study conducted in Shanghai, China. Anthropometric measures of obesity including weight, height, waist circumference, hip circumference, body mass index (BMI), waist-to-hip ratio (WHR), and waist-to-height ratio (WHtR) were evaluated. The association between WHtR, WHR, and BMI and the presence of DR was examined with logistic regression models.Results: The prevalence of DR was higher in T2D patients with high WHtR compared to those with normal WHtR (p 0.05).Conclusion: WHtR and BMI but not WHR are risk factors for DR in obese patients with T2D. Patients with high WHtR and BMI should be closely monitored to prevent the development of DR.Keywords: T2D, diabetic retinopathy, risk factor, obesity, BMI, WHR, WHtR