Comparison of the Effect of Spinal Anesthesia and General Anesthesia on Blood Glucose Concentration in Patients Undergoing Transurethral Lithotripsy

Abstract

Background and Objective: Prevention of hyperglycemia caused by surgical stress is a challenging issue. The present study was conducted to compare the effect of spinal anesthesia versus general anesthesia on blood glucose concentration in patients undergoing transurethral lithotripsy. Methods: This cross-sectional study was conducted on 58 patients undergoing transurethral lithotripsy in Imam Khomeini Hospital in Urmia. Group S included patients who chose spinal anesthesia and group G included patients who chose general anesthesia. For both groups, blood glucose and insulin concentrations were measured at different times: five minutes before induction (T1), five minutes after induction (T2), five minutes before the end of the procedure (T3) and 30 minutes after the end of the procedure (T4). Findings: The mean blood glucose in T3 (83.18±37.108) and T4 (82.16±125) in general anesthesia group was significantly higher than T3 (85.16±89.79) and T4 (72.5±10.81) in spinal anesthesia group (p<0.001). Furthermore, in the general anesthesia group, the increase in blood glucose in the time intervals T1-T2, T2-T3, T3-T4 and T1-T4 was significant (p-value: 0.03, 0.003, 0.001, <0.001, respectively). Moreover, in our study, the decrease in insulin secretion between T1 and T4 was significant only in the general anesthesia group (p=0.006). Conclusion: The results of this study showed that the spinal anesthesia method is a more preferable method to prevent the increase in blood glucose in transurethral lithotripsy.

Keywords

• spinal anesthesia
• general anesthesia
• blood glucose
• blood insulin concentration
• ureteral stone.