Canadian Journal of Kidney Health and Disease (Dec 2019)
Cultivating Innovative Pragmatic Cluster-Randomized Registry Trials Embedded in Hemodialysis Care: Workshop Proceedings From 2018
- Elliot J. Lee,
- Aakil Patel,
- Rey R. Acedillo,
- Jovina C. Bachynski,
- Ian Barrett,
- Erika Basile,
- Marisa Battistella,
- Derek Benjamin,
- David Berry,
- Peter G. Blake,
- Patricia Chan,
- Clara J. Bohm,
- Kristin K. Clemens,
- Charles Cook,
- Laura Dember,
- Jade S. Dirk,
- Stephanie Dixon,
- Elisabeth Fowler,
- Leah Getchell,
- Nazanine Gholami,
- Cory Goldstein,
- Emma Hahn,
- Betty Hogeterp,
- Susan Huang,
- Michelle Hughes,
- Meg J. Jardine,
- Shasikara Kalatharan,
- Shane Kilburn,
- Eduardo Lacson,
- Sean Leonard,
- Channing Liberty,
- Craig Lindsay,
- Jennifer M. MacRae,
- Braden J. Manns,
- Janice McCallum,
- Christopher W. McIntyre,
- Amber O. Molnar,
- Reem A. Mustafa,
- Gihad E. Nesrallah,
- Matthew J. Oliver,
- Michael Pandes,
- Sanjay Pandeya,
- Malvinder S. Parmar,
- Elijah Z. Rabin,
- Johnathan Riley,
- Samuel A. Silver,
- Jessica M. Sontrop,
- Manish M. Sood,
- Rita S. Suri,
- Navdeep Tangri,
- Daniel J. Tascona,
- Alison Thomas,
- Ron Wald,
- Michael Walsh,
- Charles Weijer,
- Matthew A. Weir,
- Hans Vorster,
- Deborah Zimmerman,
- Amit X. Garg
Affiliations
- Elliot J. Lee
- ICES, ON, Canada
- Aakil Patel
- ICES, ON, Canada
- Rey R. Acedillo
- Department of Epidemiology and Biostatistics, Western University, London, ON, Canada
- Jovina C. Bachynski
- Halton Healthcare Services, Oakville, ON, Canada
- Ian Barrett
- St. Michael’s Hospital, Toronto, ON, Canada
- Erika Basile
- Office of Human Research Ethics, Western University, London, ON, Canada
- Marisa Battistella
- Leslie Dan Faculty of Pharmacy, University of Toronto, ON, Canada
- Derek Benjamin
- Royal Victoria Regional Health Centre, Barrie, ON, Canada
- David Berry
- Algoma Regional Renal Program, Sault Area Hospital, Sault Ste. Marie, ON, Canada
- Peter G. Blake
- Ontario Renal Network, Cancer Care Ontario, Toronto, Canada
- Patricia Chan
- Division of Nephrology, Department of Medicine, Michael Garron Hospital, Toronto, ON, Canada
- Clara J. Bohm
- Department of Internal Medicine, Max Rady College of Medicine, University of Manitoba, Winnipeg, Canada
- Kristin K. Clemens
- St. Joseph’s Health Care London, ON, Canada
- Charles Cook
- Transplant Ambassador Program, Grand River Hospital, Kitchener, ON, Canada
- Laura Dember
- Renal, Electrolyte and Hypertension Division, Perelman School of Medicine, Philadelphia, PA, USA
- Jade S. Dirk
- ICES, ON, Canada
- Stephanie Dixon
- Department of Epidemiology and Biostatistics, Western University, London, ON, Canada
- Elisabeth Fowler
- The Kidney Foundation of Canada, Montreal, QC, Canada
- Leah Getchell
- Can-SOLVE CKD Network, Vancouver, BC, Canada
- Nazanine Gholami
- St. Joseph’s Health Centre, Toronto, ON, Canada
- Cory Goldstein
- Rotman Institute of Philosophy, Western University, London, ON, Canada
- Emma Hahn
- ICES, ON, Canada
- Betty Hogeterp
- Lakeridge Health Oshawa, ON, Canada
- Susan Huang
- Division of Nephrology, Department of Medicine, London Health Sciences Centre, ON, Canada
- Michelle Hughes
- Orillia Soldiers’ Memorial Hospital, ON, Canada
- Meg J. Jardine
- Innovation & Kidney Research, The George Institute for Global Health, UNSW Sydney, Newtown, NSW, Australia
- Shasikara Kalatharan
- Can-SOLVE CKD Network, Vancouver, BC, Canada
- Shane Kilburn
- ICES, ON, Canada
- Eduardo Lacson
- Tufts Medical Center, Boston, MA, USA
- Sean Leonard
- ICES, ON, Canada
- Channing Liberty
- The Ottawa Hospital, ON, Canada
- Craig Lindsay
- Scarborough Health Network, Toronto, ON, Canada
- Jennifer M. MacRae
- Division of Nephrology, Department of Medicine, University of Calgary, AB, Canada
- Braden J. Manns
- Department of Medicine, Cumming School of Medicine, University of Calgary, AB, Canada
- Janice McCallum
- Renal Services, London Health Sciences Centre, ON, Canada
- Christopher W. McIntyre
- Department of Medical Biophysics, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada
- Amber O. Molnar
- Division of Nephrology, Department of Medicine, McMaster University, Hamilton, ON, Canada
- Reem A. Mustafa
- Division of Nephrology and Hypertension, Department of Internal Medicine, University of Kansas Medical Center, Kansas City, USA
- Gihad E. Nesrallah
- Division of Nephrology, Department of Medicine, Humber River Hospital, Toronto, ON, Canada
- Matthew J. Oliver
- Division of Nephrology, Department of Medicine, University of Toronto, ON, Canada
- Michael Pandes
- Mackenzie Health, Richmond Hill, ON, Canada
- Sanjay Pandeya
- Halton Healthcare, Oakville, ON, Canada
- Malvinder S. Parmar
- Kidney Care Centre, Timmins and District Hospital, ON, Canada
- Elijah Z. Rabin
- Niagara Health System, St. Catharines, ON, Canada
- Johnathan Riley
- Ontario SPOR SUPPORT Unit, Toronto, ON, Canada
- Samuel A. Silver
- Division of Nephrology, Kingston Health Sciences Center, Queen’s University, Kingston, ON, Canada
- Jessica M. Sontrop
- Kidney Clinical Research Unit, Lawson Health Research Institute, London, ON, Canada
- Manish M. Sood
- Division of Nephrology, Department of Medicine, University of Ottawa, ON, Canada
- Rita S. Suri
- Canadian Nephrology Trials Network, Canada
- Navdeep Tangri
- Department of Internal Medicine, University of Manitoba, Winnipeg, Canada
- Daniel J. Tascona
- Orillia Soldiers’ Memorial Hospital, ON, Canada
- Alison Thomas
- St. Michael’s Hospital, Toronto, ON, Canada
- Ron Wald
- Division of Nephrology, Department of Medicine, University of Toronto, ON, Canada
- Michael Walsh
- Population Health Research Institute, Hamilton, ON, Canada
- Charles Weijer
- Rotman Institute of Philosophy, Western University, London, ON, Canada
- Matthew A. Weir
- Kidney Clinical Research Unit, Lawson Health Research Institute, London, ON, Canada
- Hans Vorster
- Ontario Renal Network, Cancer Care Ontario, Toronto, Canada
- Deborah Zimmerman
- Division of Nephrology, Department of Medicine, University of Ottawa, ON, Canada
- Amit X. Garg
- Kidney Clinical Research Unit, Lawson Health Research Institute, London, ON, Canada
- DOI
- https://doi.org/10.1177/2054358119894394
- Journal volume & issue
-
Vol. 6
Abstract
Hemodialysis is a life-sustaining treatment for persons with kidney failure. However, those on hemodialysis still face a poor quality of life and a short life expectancy. High-quality research evidence from large randomized controlled trials is needed to identify interventions that improve the experiences, outcomes, and health care of persons receiving hemodialysis. With the support of the Canadian Institutes of Health Research and its Strategy for Patient-Oriented Research, the Innovative Clinical Trials in Hemodialysis Centers initiative brought together Canadian and international kidney researchers, patients, health care providers, and health administrators to participate in a workshop held in Toronto, Canada, on June 2 and 3, 2018. The workshop served to increase knowledge and awareness about the conduct of innovative, pragmatic, cluster-randomized registry trials embedded into routine hemodialysis care and provided an opportunity to discuss and build support for new trial ideas. The workshop content included structured presentations, facilitated group discussions, and expert panel feedback. Partnerships and promising trial ideas borne out of the workshop will continue to be developed to support the implementation of future large-scale trials.
