Characteristic of Pathogens in Patients with Carbuncles and Features of Antibacterial Chemotherapy

Abstract

On the basis of the examination and treatment of 446 patients with carbuncles, it was found that the main infection germ is Staphylococcus aureus mainly in the form of monoculture. Among the singled out strains multidrugsresistant forms (MRSA) reached 13,8%. The most severe course of carbuncles was observed in patients with diabetes mellitus, but the true difference in frequency of methicillin-sensitive and methicillin-resistant staphylococcus release wasn't observed. All singled out strains MRSA have a high sensitivity to the vancomycin and linezolid. Much less frequently (9,8%) Streptococcus of group A was sown antibiotic resistance wasn't found. Microbical landscape of postcritically wounds was changing in the course of 3-4 days. Streptococcus releases such gram-negative microflora among this strains more than the half was characterized by multiantibioticresistance. Contamination of the postcritically wounds in patients that suffers from diabetes mellitus, with hospital microflora was much frequent than in patients without diabetes mellitus, frequency of the excretion of microbical associations are higher in those with diabetes (47,6%). In such situations the negative dynamic of the wound process. It shows the necessity of conduction of staged necrectomies and changes in antibacterial therapy regimens adjusted to the sensitivity of the singled out microflora.

Keywords

• carbuncles
• diabetes mellitus
• staphylococcus aureus
• antibiotic resistance