Emergence of a novel reassortant highly pathogenic avian influenza clade 2.3.4.4b A(H5N2) Virus, 2024

Rabeh El-Shesheny; Mokhtar Gomaa; Mohamed El Sayes; Mina Nabil Kamel; Ahmed El Taweel; Omnia Kutkat; Mohamed GabAllah; Amany Elkhrsawy; Hager Emam; Yassmin Moatasim; Ahmed Kandeil; Pamela P. McKenzie; Richard J. Webby; Mohamed Ahmed Ali; Ghazi Kayali

doi:10.1080/22221751.2025.2455601

Emerging Microbes and Infections (Dec 2025)

Emergence of a novel reassortant highly pathogenic avian influenza clade 2.3.4.4b A(H5N2) Virus, 2024

Rabeh El-Shesheny,
Mokhtar Gomaa,
Mohamed El Sayes,
Mina Nabil Kamel,
Ahmed El Taweel,
Omnia Kutkat,
Mohamed GabAllah,
Amany Elkhrsawy,
Hager Emam,
Yassmin Moatasim,
Ahmed Kandeil,
Pamela P. McKenzie,
Richard J. Webby,
Mohamed Ahmed Ali,
Ghazi Kayali

Affiliations

Rabeh El-Shesheny: Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza, Egypt
Mokhtar Gomaa: Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza, Egypt
Mohamed El Sayes: Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza, Egypt
Mina Nabil Kamel: Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza, Egypt
Ahmed El Taweel: Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza, Egypt
Omnia Kutkat: Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza, Egypt
Mohamed GabAllah: Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza, Egypt
Amany Elkhrsawy: Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza, Egypt
Hager Emam: Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza, Egypt
Yassmin Moatasim: Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza, Egypt
Ahmed Kandeil: Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza, Egypt
Pamela P. McKenzie: Department of Infectious Diseases, St. Jude Children’s Research Hospital, Memphis, TN, USA
Richard J. Webby: Department of Infectious Diseases, St. Jude Children’s Research Hospital, Memphis, TN, USA
Mohamed Ahmed Ali: Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza, Egypt
Ghazi Kayali: Human Link, Dubai, United Arab Emirates

DOI: https://doi.org/10.1080/22221751.2025.2455601
Journal volume & issue: Vol. 14, no. 1

Abstract

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Reassortant highly pathogenic avian influenza A(H5N2) clade 2.3.4.4.b viruses were detected from ducks and environmental samples in Egypt, June 2024. Genomic and phylogenetic analyses revealed a novel genotype produced by the reassortment of an A(H5N1) clade 2.3.3.4b virus with an A(H9N2) G1-like virus. Monitoring the spread of this virus is important.

Published in Emerging Microbes and Infections

ISSN: 2222-1751 (Online)
Publisher: Taylor & Francis Group
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Infectious and parasitic diseases; Science: Microbiology
Website: https://www.tandfonline.com/journals/temi

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Abstract

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