APOPTOTIC ACTIVITY AS A TRIGGER MECHANISM OF SYSTEMIC FIBROSIS OF INTERNAL ORGANS IN MINERS

Abstract

The subject of the study (observations). Questions of the apoptotic process in the development of fibroplastic changes in pneumoconiosis in miners. The purpose of the study – to substantiate the contribution of the genetic factor associated with genome polymorphism in the development of dust pathology in miners. Identification of gene variants as markers of individual predisposition to the development of pneumoconiosis. Research methods. Theoretical basis.

Keywords

• фибропластические изменения
• пылевая патология
• пневмокониоз
• полиморфизм генов
• апоптоз