Molecular subtypes of NPM1 mutations have different clinical profiles, specific patterns of accompanying molecular mutations and varying outcomes in intermediate risk acute myeloid leukemia

• Tamara Alpermann,
• Susanne Schnittger,
• Christiane Eder,
• Frank Dicker,
• Manja Meggendorfer,
• Wolfgang Kern,
• Christoph Schmid,
• Carlo Aul,
• Peter Staib,
• Clemens-Martin Wendtner,
• Norbert Schmitz,
• Claudia Haferlach,
• Torsten Haferlach

Affiliations

Tamara Alpermann

MLL Munich Leukemia Laboratory, Klinikum Augsburg, University of Munich, Augsburg, Germany

Susanne Schnittger

MLL Munich Leukemia Laboratory, Klinikum Augsburg, University of Munich, Augsburg, Germany

Christiane Eder

MLL Munich Leukemia Laboratory, Klinikum Augsburg, University of Munich, Augsburg, Germany

Frank Dicker

MLL Munich Leukemia Laboratory, Klinikum Augsburg, University of Munich, Augsburg, Germany

Manja Meggendorfer

MLL Munich Leukemia Laboratory, Klinikum Augsburg, University of Munich, Augsburg, Germany

Wolfgang Kern

MLL Munich Leukemia Laboratory, Klinikum Augsburg, University of Munich, Augsburg, Germany

Christoph Schmid

Department of Hematology and Oncology, Klinikum Augsburg, University of Munich, Augsburg, Germany

Carlo Aul

Department of Hematology and Oncology, Helios St. Johannes Klinik, Duisburg, Germany

Peter Staib

Department of Hematology and Oncology, St. Antonius Hospital, Eschweiler, Germany

Clemens-Martin Wendtner

Department of Hematology, Oncology, Immunology, Palliative Care, Infectious Diseases and Tropical Medicine, Klinikum Schwabing, Munich, Germany

Norbert Schmitz

Department of Hematology, Oncology and Stem Cell Transplantation, Asklepios Klinik St. Georg, Hamburg, Germany

Claudia Haferlach

MLL Munich Leukemia Laboratory, Klinikum Augsburg, University of Munich, Augsburg, Germany

Torsten Haferlach

MLL Munich Leukemia Laboratory, Klinikum Augsburg, University of Munich, Augsburg, Germany