704 Global identification of lupus genetic risk variants modulating the type I interferon pathway through CRISPR-based genomic screening

• Guojun Hou,
• Nan Shen,
• Xinyi Zhu,
• Yutong Zhang,
• Zhaorui Cheng

Affiliations

Guojun Hou

Shanghai Institute of Rheumatology, Renji Hospital, Shanghai Jiao Tong University School of Medicine (SJTUSM), Shanghai, China

Nan Shen

2Center of Autoimmune Genomics and Etiology, Division of Human Genetics, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, USA

Xinyi Zhu

Shanghai Institute of Rheumatology, Renji Hospital, Shanghai Jiao Tong University School of Medicine (SJTUSM), China

Yutong Zhang

Shanghai Institute of Rheumatology, Renji Hospital, Shanghai Jiao Tong University School of Medicine (SJTUSM), China

Zhaorui Cheng

Shanghai Institute of Rheumatology, Renji Hospital, Shanghai Jiao Tong University School of Medicine (SJTUSM), China