CHIMIA (Apr 2004)

New Catalysts and Receptors by Self-Assembly and Combinatorial Chemistry

  • Kay Severin

DOI
https://doi.org/10.2533/000942904777677948
Journal volume & issue
Vol. 58, no. 4

Abstract

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New methods that allow the generation of transition metal-based catalysts and receptors are discussed. It is shown that heterobimetallic, halogeno-bridged complexes are well-suited for screening assays in combinatorial catalysis. Metal catalysts with a structurally defined second coordination sphere can be obtained by molecular imprinting with pseudo-substrate conjugates as exemplified by the substrate-, regio- and stereoselective reduction of ketones, catalyzed by immobilized ruthenium and rhodium complexes. Macrocyclic complexes, formed by self-assembly of organometallic complexes, are shown to act as highly specific receptors for small cations and anions.

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