Nature Communications (Aug 2021)

Protein interface redesign facilitates the transformation of nanocage building blocks to 1D and 2D nanomaterials

  • Xiaorong Zhang,
  • Yu Liu,
  • Bowen Zheng,
  • Jiachen Zang,
  • Chenyan Lv,
  • Tuo Zhang,
  • Hongfei Wang,
  • Guanghua Zhao

DOI
https://doi.org/10.1038/s41467-021-25199-x
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 11

Abstract

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Various strategies to assemble protein building blocks into one-, two- and three-dimensional hierarchical nanostructures were described, but controlling the transformation between those different assemblies is largely uninvestigated. Here, the authors describe a protein interface redesign strategy and use it for the self-assembly transformation of dimeric building blocks from hollow protein nanocage to filament, nanorod and nanoribbon.