Indian Journal of Pathology and Microbiology (Jan 2024)

Interfollicular Hodgkin's lymphoma: A diagnostic challenge for pathologists

  • Maneesh K Vijay,
  • Neha Sethi

DOI
https://doi.org/10.4103/ijpm.ijpm_641_22
Journal volume & issue
Vol. 67, no. 1
pp. 214 – 216

Abstract

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Interfollicular Hodgkin's lymphoma (IFHL) is a rare pattern of classical Hodgkin's lymphoma (CHL) showing reactive follicular hyperplasia with involvement of the interfollicular area by HL. Two cases are reported in this study having primary IFHL out of total of 500 cases of CHL reported at our center. Diagnosis of IFHL was made on the basis of morphological and immunohistochemical features. As they represent an early stage of the disease, their identification and awareness s very important to get proper treatment at its earliest. This variant is very unusual and is diagnostically challenging for pathologists.

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