Secretory Leukocyte Protease Inhibitor in Preterm Labor and Pregnancy

Abstract

Objective: To investigate the levels of secretory leukocyte protease inhibitor (SLPI) in women with preterm labor and pregnancy. Methods: SLPI level examination conducted to 32 samples of pregnant women who meet the inclusion and exclusion criteria, consists of 16 preterm labor and 16 preterm pregnancy. Sample analysis carried out in Prodia Laboratory Jakarta. SLPI level examination used ELISA method. The obtained data processed by SPSS software version 20.0 and discussed with existing literature theory. Results: Mean plasma SLPI level in patients with preterm labor is 30.319 ng/ml and median: 29.950 ng/ml with p value: 0.652, while the mean on preterm pregnancy is 45.975 ng/ml and median: 41.600 ng/ml with p value: 0.005. Conclusion: There are significant differences of SLPI level between preterm labor and preterm pregnancy. Keywords: preterm labor, preterm pregnancy, SLPI