Bilateral perisylvian syndrome management and drug-related problems

Abstract

Perisylvian syndrome is a noncurable condition characterized by polymicrogyria in the perisylvian or perirolandic region. Perisylvian means the region or area of the brain that is responsible for language. The bilateral perisylvian syndrome is a congenital neurological condition marked by abnormal neuron distribution in the cortex. We report the case of a 21-year-old female patient with the complaints of recurrent generalized clonic–tonic seizures with intellectual development disorder, loss of consciousness (5–10 min), blurring of vision, poor academic performance, slurring of speech, and history of clubfoot. An intelligence quotient assessment was conducted, and the result showed borderline intelligence. She was diagnosed with a case of bilateral perisylvian syndrome with recurrent seizure disorder with intellectual development disorder and she was treated with anticonvulsant medications.

Keywords

• anticonvulsants toxicity
• bilateral perisylvian syndrome
• corpus callosotomy
• intellectual development disorder
• seizures