Акушерство, гинекология и репродукция (Aug 2016)
TREATMENT FOR THE UROGENITAL DISORDERS, CAUSED BY THE ESTROGEN DEFICIENCY
Abstract
Urogenital disorders (UD) are the common complication of the climacteric syndrome: itching, burning, soreness, vaginal dryness, painful coitus, frequent urinary urgency, urination past bed time, incontinence and poor capability to withhold the urine, worsen the quality of life for almost half of the women in post menopause. The key factor that leads to the urogenital disorders in post menopause is the low estrogen synthesis. An efficient and safe way to prevent and treat these disorders is to use the forms of the estriol for the local application. Key factor, that differentiates estriol from the other estrogens, is that estriol selectively binds with the receptor-cell of the urogenital tract for 2-4 hours, when used in local application and so does not have any systemic effect on target-organs, in particular does not affect endometrium and myometrium. In this article we have presented the survey of publications and the result from the personal UD (Urogenital disorders) treatment observation caused by the estrogen deficiency. For the treatment we used: Ovestin (Овестин®) in cream and suppository, containing estriol as the active component. We also described all the pharmacoeconomic properties of the Ovestin and the beneficial effect the local application of estriol has on a married couple.