Comparison of Lidocaine-Distilled Water and Lidocaine-Mgso4 Mixture in Epidural Anesthesia of Dog

Abstract

Objective- To compare the lidocaine-MgSO4 combination with lidocaine-Distilled water inthe epidural of indigenous awake dogs.Design- Prospective experimental study.Animals- Five young (12±2 months) female indigenous dogs weighting (10.74 ± 0.44 kg).Procedures- Epidural anesthesia was produced in all dogs with 2% lidocaine (1ml/4.5 kgbody weight) with 1 ml distilled water and two weeks later repeated by lidocaine (1ml/4.5kg) with 1 ml of 10% MgSO4. Time to recumbency, onset time, duration of analgesia andcranial spread of analgesia and standing time were recorded. Heart rate, Respiratory rateand body temperature were recorded at 0 minute prior to epidural administration of eachtreatment as a base line values and at 5, 10, 15, 30, 60 and 75 minutes afterwards. Statisticalanalysis included paired student t-test and ANOVA (Spss, soft ware of windows). p