Cardiovascular Risk Factors, Angiographical Features and Short-Term Prognosis of Acute Coronary Syndrome in People Living with Human Immunodeficiency Virus: Results of a Retrospective Observational Multicentric Romanian Study
Mircea Bajdechi,
Adriana Gurghean,
Vlad Bataila,
Alexandru Scafa-Udriste,
Roxana Radoi,
Anca Cristiana Oprea,
Adrian Marinescu,
Stefan Ion,
Valentin Chioncel,
Alina Nicula,
Achilleas Anastasiou,
Georgiana-Elena Bajdechi,
Ilinca Savulescu-Fiedler,
Irina Magdalena Dumitru,
Sorin Rugina
Affiliations
Mircea Bajdechi
Faculty of Medicine, University of Medicine and Pharmacy “Carol Davila” of Bucharest, 050474 Bucharest, Romania
Adriana Gurghean
Faculty of Medicine, University of Medicine and Pharmacy “Carol Davila” of Bucharest, 050474 Bucharest, Romania
Vlad Bataila
Emergency Clinical Hospital of Bucharest, 014461 Bucharest, Romania
Alexandru Scafa-Udriste
Faculty of Medicine, University of Medicine and Pharmacy “Carol Davila” of Bucharest, 050474 Bucharest, Romania
Roxana Radoi
Clinical Hospital of Infectious and Tropical Disease “Dr. Victor Babes” of Bucharest, 030303 Bucharest, Romania
Anca Cristiana Oprea
Faculty of Medicine, University of Medicine and Pharmacy “Carol Davila” of Bucharest, 050474 Bucharest, Romania
Adrian Marinescu
National Institute of Infectious Disease “Prof. Dr. Matei Bals” of Bucharest, 021105 Bucharest, Romania
Stefan Ion
Faculty of Medicine, “Titu Maiorescu” University of Bucharest, 040441 Bucharest, Romania
Valentin Chioncel
Faculty of Medicine, University of Medicine and Pharmacy “Carol Davila” of Bucharest, 050474 Bucharest, Romania
Alina Nicula
Faculty of Medicine, University of Medicine and Pharmacy “Carol Davila” of Bucharest, 050474 Bucharest, Romania
Achilleas Anastasiou
Departament of Statistics and Actuarial-Financial Mathematics, Laboratory of Statistics and Data Analysis, University of Aegean, 83200 Samos, Greece
Georgiana-Elena Bajdechi
Faculty of Medicine, University of Medicine and Pharmacy “Carol Davila” of Bucharest, 050474 Bucharest, Romania
Ilinca Savulescu-Fiedler
Faculty of Medicine, University of Medicine and Pharmacy “Carol Davila” of Bucharest, 050474 Bucharest, Romania
Irina Magdalena Dumitru
Doctoral School of Medicine, “Ovidius” University of Constanta, 900470 Constanta, Romania
Sorin Rugina
Doctoral School of Medicine, “Ovidius” University of Constanta, 900470 Constanta, Romania
People living with human immunodeficiency virus have increased cardiovascular risk due to a higher prevalence of traditional and particular risk factors such as chronic inflammation, immune dysregulation, endothelial dysfunction, coagulation abnormalities and antiretroviral therapy. In developed countries, coronary artery disease has become the most frequent cardiovascular disease and an important cause of mortality in these patients. The symptomatology of an acute coronary syndrome can be atypical, and the prevalence of each type of acute coronary syndrome is reported differently. Regarding coronary artery disease severity in people living with HIV, the literature data indicates that the presence of single-vessel disease is akin to that of HIV-negative patients, and their short-term prognosis is unclear. This study aims to assess the clinical characteristics, biological parameters, angiographical features and short-term prognosis of acute coronary syndrome in a cohort of Romanian people living with human immunodeficiency virus.
