Optimization of the method for predicting clinical outcomes of reactive arthritis in children

Abstract

The comparative analysis of content of cytokine and significant local antimicrobial factors (IL-6, IL-8, IL-17, INF-γ, TNF-α, IL-10, CRP, lysozyme, lactoferrin) in the coprofiltrates and serum of patients with acute and chronic reactive arthritis (ReA) made it possible to determine the markers predicting the course and outcomes of arthritis. It is established that the method of predicting ReA involving the analysis of the parameters characterizing coprofiltrates of children is the more accurate and effective method.

Keywords

• reactive arthritis
• coprofiltrates
• blood serum
• lactoferrin
• lysozyme
• cytokines
• c-reactive protein