POSTOPERATIVE ADJUVANT RADIATION THERAPY IN MALE BREAST CANCER: RETROSPECTIVE EVALUATION

Abstract

Introduction:Male breast cancer is accounting less than 1% of all breast cancer cases. Evaluation of charactheristics, treatment response and possible prognostic factors of irradiated (RT) male patients with breast cancer was aimed.Materials and methods:Twelve adult male with breast cancer patients records, treated between 1999 and 2006 were evaluated retrospectively. Disease free survival (DFS) was performed from end of RT.Results:Mean age of patients were 59. Application complaint was painless mass under the areola in all of them. Pathological diagnosis were done after excisional biopsy in the nine patients, after mastectomy in the three of them. In the seven patients lesion was localised in the left breast. Radical modifi ed mastectomy was performed to the eight patients, simple mastectomy to the four of all and axillary dissection were added to the two of these. ER was positive in the nine patients, PR was positive in the eight patients. Two of all had a family history. Median dose of postoperative adjuvant RT was 56 Gy. Median followup was 6.4 years. Median DFS was 4,12 years. DFS rate for 2 years was 6%. DFS rate for 5 years was 65%. During follow-up, local recurrens was evaluated in the one patient and distant metastasis in the four patients.Discussion:Although none of the prognostic factors mentioned in the literature presented signifi cant, unfavorable eff ects of the positivity of lymph node and performing simple mastectomy was observed on disease free survival.

Keywords

• male
• breast cancer
• radiotherapy