Incidental Prostate Adenocarcinoma in Prostate Transurethral Resections: Our Eight Year Experience

Abstract

Objective:Incidental early-stage prostate cancer (PC) can be detected in patients undergoing transurethral resection of the prostate (TURP) due to benign prostatic hyperplasia (BPH). In our study, we investigated the incidence of incidental PC and the relationship of the incidence of PC with age, serum prostate specific antigen (PSA) levels and resected prostate tissue volume in patients undergoing TURP for BPH.Materials and Methods:A total of 391 patients, who underwent TURP for BPH in our hospital between 2011 and 2018, were included in the study. Age and volumes of resection materials of the cases were obtained from pathology reports and blood PSA levels were obtained from the urology clinic.Results:In our series, incidental PC was detected in 17 of 391 cases (4.3%). The mean age of the patients with and without tumor was 74.5 years 69.5 years, respectively. The mean preoperative PSA level was 5.05 ng/mL in 226 patients without PC and the mean preoperative PSA level was 4.46 ng/mL in 15 patients with PC whose preoperative PSA levels could be checked by the urology clinic.Conclusion:In our study, incidental PC detection rate (<5%) in surgical specimens of patients undergoing TURP for BPH was found to be compatible with the literature. The incidence of PC was found to be higher, especially in patients aged 70 years and older. In these patients, preoperative serum PSA levels were lower than those without tumor. histopathological examination of all TURP materials, especially those obtained in patients of advanced age undergoing TURP with, a preliminary diagnosis of BPH, are important in terms of avoiding underdiagnosis.

Keywords

• incidental
• prostate carcinoma
• transurethral resection of the prostate