Clinical evaluation of the Simplexa HSV 1 &amp; 2 Direct assay for bronchoalveolar lavage specimens

Tung Phan; David Gerlowski; Melissa McCullough; Jamie Gribschaw; William Pasculle; Alan Wells

Journal of Clinical Virology Plus (Jun 2024)

Clinical evaluation of the Simplexa HSV 1 & 2 Direct assay for bronchoalveolar lavage specimens

Tung Phan,
David Gerlowski,
Melissa McCullough,
Jamie Gribschaw,
William Pasculle,
Alan Wells

Affiliations

Tung Phan: Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15213, USA; Corresponding author.
David Gerlowski: Clinical Microbiology Laboratory, UPMC Hospital System, Pittsburgh, PA 15261, USA
Melissa McCullough: Clinical Microbiology Laboratory, UPMC Hospital System, Pittsburgh, PA 15261, USA
Jamie Gribschaw: Clinical Microbiology Laboratory, UPMC Hospital System, Pittsburgh, PA 15261, USA
William Pasculle: Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15213, USA
Alan Wells: Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15213, USA

Journal volume & issue: Vol. 4, no. 2
p. 100177

Abstract

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Rapid laboratory testing is essential to detect HSV in the lower respiratory tract to allow rapid treatment decisions. We evaluated the clinical performance of the Simplexa HSV 1 & 2 Direct assay in bronchoalveolar lavage. This assay is highly sensitive and specific in detecting HSV-1 and HSV-2 in bronchoalveolar lavage.

Published in Journal of Clinical Virology Plus

ISSN: 2667-0380 (Online)
Publisher: Elsevier
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Infectious and parasitic diseases
Website: https://www.journals.elsevier.com/journal-of-clinical-virology-plus

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