CNS Oncology (Apr 2018)

Intracranial meningioma with carcinoma tumor-to-tumor metastasis: two case reports

  • Jason T Pham,
  • Ronald C Kim,
  • Anna Nguyen,
  • Daniela Bota,
  • Xiao-Tang Kong,
  • Sumeet Vadera,
  • Frank Hsu,
  • Jose A Carrillo

DOI
https://doi.org/10.2217/cns-2017-0022
Journal volume & issue
Vol. 7, no. 2

Abstract

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Meningiomas have been implicated as the most common primary intracranial tumor to contain tumor-to-tumor metastasis. In the following two case reports, we describe cases of adenocarcinoma and breast carcinoma that metastasized into an intracranial meningioma. The first patient was a 64-year-old man presenting to the emergency department with seizures and loss of consciousness. After a left frontal mass resection, pathology reported a heterogeneous mass consisting of a meningioma and a metastatic adenocarcinoma component. The second patient was a 63-year-old woman presenting with significant vision problems and unstable gait. After a right frontal mass resection, pathology reported a heterogeneous mass consisting of a meningioma and a metastatic breast carcinoma component. Possible explanations for the development of the tumor-to-tumor metastasis are described.

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