The lack of association between different LDL‐C levels and oxidized LDL in patients with type 2 diabetes

Abstract

Abstract Background High concentrations of low‐density lipoprotein cholesterol (LDL‐C) have been a known risk factor for cardiovascular diseases. Also, the role of oxidized LDL (ox‐LDL) in forming atherosclerosis plaque has been proven. However, it has not yet been proven that atherogenic LDL‐C by‐products like ox‐LDL will decrease by keeping the LDL levels at the desired level. This study aimed to examine the relationship between LDL‐C and ox‐LDL in different LDL‐C values in patients with type 2 diabetes (T2D). Methods In this cross‐sectional study, 347 patients with T2D who received statins were enrolled. LDL‐C values were defined into four groups as LDL‐C 100 mg/dL in patients with T2D. However, the revealed association of ox‐LDL with TG level and TG/HDL ratio may be considered in the clinic.

Keywords

• atherosclerosis
• diabetes mellitus
• lipids
• lipoproteins
• low‐density lipoprotein
• oxidized LDL