A case of respiratory infection possibly caused by Mycobacterium triviale: Current problems on diagnostic and therapeutic strategies

Asako Okabayashi, MD; Mizue Hasegawa, MD, PhD; Akitoshi Sato, MD; Hideki Katsura, MD, PhD; Toshiko Kamata, MD, PhD; Eitetsu Koh, MD, PhD; Yasuo Sekine, MD, PhD

doi:10.1016/j.rmcr.2017.04.012

Respiratory Medicine Case Reports (Jan 2017)

A case of respiratory infection possibly caused by Mycobacterium triviale: Current problems on diagnostic and therapeutic strategies

Asako Okabayashi, MD,
Mizue Hasegawa, MD, PhD,
Akitoshi Sato, MD,
Hideki Katsura, MD, PhD,
Toshiko Kamata, MD, PhD,
Eitetsu Koh, MD, PhD,
Yasuo Sekine, MD, PhD

Affiliations

Asako Okabayashi, MD: Divisions of Respiratory Medicine, Tokyo Women's Medical University Yachiyo Medical Center, 477-96 Owadashinden, Yachiyo City, Chiba, 276-8524, Japan
Mizue Hasegawa, MD, PhD: Divisions of Respiratory Medicine, Tokyo Women's Medical University Yachiyo Medical Center, 477-96 Owadashinden, Yachiyo City, Chiba, 276-8524, Japan
Akitoshi Sato, MD: Divisions of Respiratory Medicine, Tokyo Women's Medical University Yachiyo Medical Center, 477-96 Owadashinden, Yachiyo City, Chiba, 276-8524, Japan
Hideki Katsura, MD, PhD: Divisions of Respiratory Medicine, Tokyo Women's Medical University Yachiyo Medical Center, 477-96 Owadashinden, Yachiyo City, Chiba, 276-8524, Japan
Toshiko Kamata, MD, PhD: Divisions of Thoracic Surgery, Tokyo Women's Medical University Yachiyo Medical Center, 477-96 Owadashinden, Yachiyo City, Chiba, 276-8524, Japan
Eitetsu Koh, MD, PhD: Divisions of Thoracic Surgery, Tokyo Women's Medical University Yachiyo Medical Center, 477-96 Owadashinden, Yachiyo City, Chiba, 276-8524, Japan
Yasuo Sekine, MD, PhD: Divisions of Thoracic Surgery, Tokyo Women's Medical University Yachiyo Medical Center, 477-96 Owadashinden, Yachiyo City, Chiba, 276-8524, Japan

DOI: https://doi.org/10.1016/j.rmcr.2017.04.012
Journal volume & issue: Vol. 21, no. C
pp. 138 – 141

Abstract

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Mycobacterium triviale is a subspecies of the Mycobacterium terrae complex, which rarely causes disease in humans. We encountered a case of respiratory infection, possibly caused by M. triviale, which was successfully treated by levofloxacin and clarithromycin. Although DNA-DNA hybridization identified M. triviale in one of three samples, clinical validations convinced us that it was the pathogen. 16s ribosomal RNA sequencing would have been reliable and ideal to perform in this case, although it is not covered by the insurance system in Japan. Nevertheless, this experience remains to be instructive because the clinical course, guidelines on the diagnosis, and therapeutic strategies for respiratory infections caused by M. triviale are not well-known or have not been established. Awareness of the possibility of respiratory infections caused by M. triviale and further collection and analysis of its predisposing conditions are essential.

Published in Respiratory Medicine Case Reports

ISSN: 2213-0071 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the respiratory system
Website: http://www.journals.elsevier.com/respiratory-medicine-case-reports/

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