Journal of Vascular Surgery Cases and Innovative Techniques (Feb 2025)

Epithelioid hemangioendothelioma involving the superficial femoral artery and femoral vein

  • Rachad Wehbe, MD,
  • Xi Wang, BMed,
  • Karina A. Newhall, MD, MS,
  • Michael C. Stoner, MD,
  • Doran S. Mix, MD,
  • Grayson S. Pitcher, MD

Journal volume & issue
Vol. 11, no. 1
p. 101645

Abstract

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Epithelioid hemangioendothelioma (EHE) is a rare vascular tumor. We present the case of a 64-year-old woman who presented with new-onset claudication and an atypical vascular mass involving the superficial femoral artery and femoral vein. En bloc resection and vascular reconstruction was performed which revealed a G1 EHE involving the walls of the superficial femoral artery and femoral vein with tumor cells positive for ERG-, CD31, and CAMTA-1. We discuss the preoperative workup for atypical vascular masses and the challenges associated with EHE.

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