mSphere
(Aug 2021)
A New Contact Killing Toxin Permeabilizes Cells and Belongs to a Broadly Distributed Protein Family
Cristian V. Crisan,
Harshini Chandrashekar,
Catherine Everly,
Gabi Steinbach,
Shannon E. Hill,
Peter J. Yunker,
Raquel R. Lieberman,
Brian K. Hammer
Affiliations
Cristian V. Crisan
School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA
Harshini Chandrashekar
Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Catherine Everly
School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA
Gabi Steinbach
Center for Microbial Dynamics and Infection, Georgia Institute of Technology, Atlanta, Georgia, USA
Shannon E. Hill
Parker H. Petit Institute for Bioengineering & Bioscience, Georgia Institute of Technology, Atlanta, Georgia, USA
Peter J. Yunker
Center for Microbial Dynamics and Infection, Georgia Institute of Technology, Atlanta, Georgia, USA
Raquel R. Lieberman
Parker H. Petit Institute for Bioengineering & Bioscience, Georgia Institute of Technology, Atlanta, Georgia, USA
Brian K. Hammer
ORCiD School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA
DOI
https://doi.org/10.1128/mSphere.00318-21
Journal volume & issue
Vol. 6,
no. 4
Abstract
Read online
Bacteria live in polymicrobial communities where competition for resources and space is essential for survival. Proteobacteria use the T6SS to eliminate neighboring cells and cause disease.
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