A New Contact Killing Toxin Permeabilizes Cells and Belongs to a Broadly Distributed Protein Family

Cristian V. Crisan; Harshini Chandrashekar; Catherine Everly; Gabi Steinbach; Shannon E. Hill; Peter J. Yunker; Raquel R. Lieberman; Brian K. Hammer

doi:10.1128/mSphere.00318-21

mSphere (Aug 2021)

A New Contact Killing Toxin Permeabilizes Cells and Belongs to a Broadly Distributed Protein Family

Cristian V. Crisan,
Harshini Chandrashekar,
Catherine Everly,
Gabi Steinbach,
Shannon E. Hill,
Peter J. Yunker,
Raquel R. Lieberman,
Brian K. Hammer

Affiliations

Cristian V. Crisan: School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA
Harshini Chandrashekar: Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Catherine Everly: School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA
Gabi Steinbach: Center for Microbial Dynamics and Infection, Georgia Institute of Technology, Atlanta, Georgia, USA
Shannon E. Hill: Parker H. Petit Institute for Bioengineering & Bioscience, Georgia Institute of Technology, Atlanta, Georgia, USA
Peter J. Yunker: Center for Microbial Dynamics and Infection, Georgia Institute of Technology, Atlanta, Georgia, USA
Raquel R. Lieberman: Parker H. Petit Institute for Bioengineering & Bioscience, Georgia Institute of Technology, Atlanta, Georgia, USA
Brian K. Hammer: ORCiD; School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA

DOI: https://doi.org/10.1128/mSphere.00318-21
Journal volume & issue: Vol. 6, no. 4

Abstract

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Bacteria live in polymicrobial communities where competition for resources and space is essential for survival. Proteobacteria use the T6SS to eliminate neighboring cells and cause disease.

Published in mSphere

ISSN: 2379-5042 (Online)
Publisher: American Society for Microbiology
Country of publisher: United States
LCC subjects: Science: Microbiology
Website: https://journals.asm.org/journal/msphere

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