Synthesis of New Racemic α,α-Diaminocarboxylic Ester Derivatives

Abstract

New racemic methyl or ethyl α-aminoglycinate derivatives were synthesized by N-alkylation of amines (aniline, 4-methylaniline, 2-methylaniline, 2,4-dimethoxyaniline, 2-nitroaniline, 4-chloro-2-fluoroaniline, 2-naphthylamine, benzylamine, N,N-dibenzylamine, and cyclohexylamine) with methyl or ethyl α-azidoglycinate.

Keywords

• amine
• N-alkylation
• methyl α-azidoglycinate
• α-amino acids