The Effect of Foliar Application of Urea and Salicylic Acid on the Antibacterial Properties of Physalis alkekengi L. In vitro condition

Ali  Pezeshki; Hassan  Nourafcan; Mehdi  Oraei; Naser  Mohebalipour; Assad  Assadi

doi:10.22087/hmj.v7i3.847

Herbal Medicines Journal (Dec 2022)

The Effect of Foliar Application of Urea and Salicylic Acid on the Antibacterial Properties of Physalis alkekengi L. In vitro condition

Ali Pezeshki,
Hassan Nourafcan,
Mehdi Oraei,
Naser Mohebalipour,
Assad Assadi

Affiliations

Ali Pezeshki: Department of Agriculture, Faculty of Agriculture, Miyaneh Branch, Islamic Azad University, Miyaneh, Iran
Hassan Nourafcan: Department of Agriculture, Medicinal Plants and Organic Products Research Center, Miyaneh Branch, Islamic Azad University, Miyaneh, Iran
Mehdi Oraei: Department of Horticultural Sciences, Faculty of Agriculture, Miyaneh Branch, Islamic Azad University, Miyaneh, Iran
Naser Mohebalipour: Department of Agriculture, Faculty of Agriculture, Miyaneh Branch, Islamic Azad University, Miyaneh, Iran
Assad Assadi: Department of Veterinary Medicine, Faculty of veterinary, Medicinal Plants and Organic Products Research Center, Miyaneh Branch, Islamic Azad University, Miyaneh, Iran

DOI: https://doi.org/10.22087/hmj.v7i3.847
Journal volume & issue: Vol. 6, no. 3

Abstract

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Background and Aim: The Physalis alkekengi is a medicinal plant that has long been used in pharmaceutical, food and health products. Increasing and indiscriminate use of synthetic antibiotics against bacterial infections has increased drug resistance. As a result, today there is an increasing tendency among people to use drugs of natural origin, particularly herbal ones. In this regard, this study was conducted to investigate the antibacterial effects of alcoholic extract of Physalis alkekengi on some common bacteria in vitro condition. Materials and Methods: In this study, the alcoholic extract of Physalis alkekengi obtained from foliar application of urea fertilizer (0.25, 0.5, 1 and 2%) and salicylic acid (0.001. 0.0025, 0.005 and 0.01 mM) at four levels were used. For this purpose, antibacterial effects of the extracts were investigated by dilution methods in tube, disk and well diffusion method against Staphylococcus aureus, Escherichia coli, Salmonella enterica, Proteus mirabilis, Pseudomonas aeruginosa, Bacillus cereus, Shigella dysenteriae and Klebsiella pneumonia. Results: The results of the present study indicated that the extracts of Physalis alkekengi have antibacterial effects under the influence of different treatments of urea and salicylic acid. Moreover, the results showed the effects of minimum inhibitory concentration and minimum bactericidal concentrations of different treatments of urea and salicylic acid. Among the tested concentrations, urea concentrations of 2% and 0.5% had the highest and lowest inhibitory effects on bacterial growth compared to the negative and positive control groups respectively. Salicylic acid with 0.01 and 0.001mM showed the highest and lowest bacterial growth inhibitory effects respectively. Conclusion: The results of this study showed that the extract of Physalis alkekengi contain suitable antibacterial substances that can be used as an alternative in cases of drug resistance against pathogenic microorganisms.

Physalis alkekengi, Dilution tube, Well diffusion, Disk diffusion, MIC, MBC

Published in Herbal Medicines Journal

ISSN: 2538-2144 (Online)
Publisher: Lorestan University of Medical Sciences
Country of publisher: Iran, Islamic Republic of
LCC subjects: Medicine: Pharmacy and materia medica
Website: http://hmj.lums.ac.ir

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