Design, Synthesis, and Biological Evaluation of Darunavir Analogs as HIV‑1 Protease Inhibitors

• Muhammad Asad Ur Rehman,
• Hathaichanok Chuntakaruk,
• Soraat Amphan,
• Aphinya Suroengrit,
• Kowit Hengphasatporn,
• Yasuteru Shigeta,
• Thanyada Rungrotmongkol,
• Kuakarun Krusong,
• Siwaporn Boonyasuppayakorn,
• Chanat Aonbangkhen,
• Tanatorn Khotavivattana

Affiliations

Muhammad Asad Ur Rehman

Center of Excellence in Natural Products Chemistry, Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok, Thailand

Hathaichanok Chuntakaruk

Center of Excellence in Structural and Computation Biology, Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok, Thailand

Soraat Amphan

Center of Excellence in Structural and Computation Biology, Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok, Thailand

Aphinya Suroengrit

Center of Excellence in Applied Medical Virology, Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand

Kowit Hengphasatporn

Center for Computational Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan

Yasuteru Shigeta

Center for Computational Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan

Thanyada Rungrotmongkol

Center of Excellence in Structural and Computation Biology, Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok, Thailand

Kuakarun Krusong

Center of Excellence in Structural and Computation Biology, Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok, Thailand

Siwaporn Boonyasuppayakorn

Center of Excellence in Applied Medical Virology, Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand

Chanat Aonbangkhen

Center of Excellence in Natural Products Chemistry, Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok, Thailand

Tanatorn Khotavivattana

Center of Excellence in Natural Products Chemistry, Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok, Thailand