Medicina (Nov 2016)

Increased chance of metabolic syndrome in women living with HIV/AIDS and lipodystrophic syndrome

  • Thiago Cândido Alves,
  • Camila de Moraes,
  • André Pereira dos Santos,
  • Ana Cláudia Rossini Venturini,
  • Rodrigo de Carvalho Santana,
  • Anderson Marliere Navarro,
  • Dalmo Roberto Lopes Machado

DOI
https://doi.org/10.11606/issn.2176-7262.v49i5p421-428
Journal volume & issue
Vol. 49, no. 5

Abstract

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Study design: cross-sectional and prevalence study. Objective: compare symptoms criteria for Metabolic Syndrome (MS) in men and women living with HIV/aids, patients with lipodystrophy syndrome on antiretroviral therapy. Method: Forty-one patients of both sexes (18-69 years), from an exercise guidance program as alternative therapy. They had their body composition (DXA), height, weight, abdomen circumference, and lipid profile, blood glucose, blood pressure, and CD4+ count, determined. The IDF criteria for diagnosis of MS were used. Results: Women showed greater relative fat (p = 0.001), central obesity (p = 0.005), total cholesterol (p = 0.043) and LDL cholesterol (p = 0.034), and CD4+ count (p = 0.034) when compared to men. The mean values for both sexes showed high levels of triglycerides (> 211.4 mg.dL-1) and low HDL (< 39.5 mg.dL-1). The prevalence ratio of MS was twice in women than men (p = 0.005). Conclusion: The prevalence ratio (PR = 0.465) of sex metabolic syndrome-associated, shown that woman patients have higher relative risk and therefore require alternative actions to reduce the chances of developing this syndrome

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