Química Nova (Jan 2014)

Phytochemical investigation of Wissadula periplocifolia (L.) C. Presl and evaluation of its antibacterial activity

  • Yanna C. F. Teles,
  • Roosevelt A. Gomes,
  • Micaelly da S. Oliveira,
  • Kaio L. de Lucena,
  • José S. do Nascimento,
  • Maria de Fátima Agra,
  • John O. Igoli,
  • Alexander I. Gray,
  • Maria de Fátima V. de Souza

DOI
https://doi.org/10.5935/0100-4042.20140238
Journal volume & issue
Vol. 37, no. 9
pp. 1491 – 1495

Abstract

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A phytochemical study on the aerial parts of Wissadula periplocifolia using chromatographic techniques has led to the isolation of sitosterol (1a), stigmasterol (1b), sitosterol 3-O-β-D-glucopyranoside (2a), stigmasterol 3-O-β-D-glucopyranoside (2b), phaeophytin A (3), 13²-hydroxy-(13²-S)-phaeophytin A (4), phaeophytin B (5), 17³-ethoxyphaeophorbide (6), 3,4-seco-urs-4(23),20(30)-dien-3-oic acid (7), 3-oxo-21β-H-hop-22(29)-ene (8), dammaradienone (9a), and taraxastenone (9b). The isolated compounds were characterised by spectroscopic analysis. A preliminary assay to evaluate the antibacterial activity of W. periplocifolia extracts and fractions showed that the dichloromethane, ethyl acetate, and n-butanol fractions were active against Enterococcus faecalis.

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