Nature Communications (May 2021)

Non-invasive, opsin-free mid-infrared modulation activates cortical neurons and accelerates associative learning

  • Jianxiong Zhang,
  • Yong He,
  • Shanshan Liang,
  • Xiang Liao,
  • Tong Li,
  • Zhi Qiao,
  • Chao Chang,
  • Hongbo Jia,
  • Xiaowei Chen

DOI
https://doi.org/10.1038/s41467-021-23025-y
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 9

Abstract

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Neurostimulant drugs or magnetic/electrical stimulation techniques have shown limited effects on learning capabilities of healthy subjects. The authors show that, without introducing an exogeneous gene, mid-infrared light can modulate firing activity of neurons in vivo and accelerate learning in mice.