Journal of Dermatology and Dermatologic Surgery (Jan 2017)

Successful use of combined corticosteroids and rituximab in a patient with refractory cutaneous polyarteritis nodosa

  • Ibrahim A. Al-Homood,
  • Mohammad A. Aljahlan

DOI
https://doi.org/10.1016/j.jdds.2016.05.004
Journal volume & issue
Vol. 21, no. 1
pp. 24 – 26

Abstract

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Cutaneous polyarteritis nodosa is a rare subtype of polyarteritis nodosa that lacks significant internal organ involvement. It has a relapsing remitting nature and usually is less responsive to conventional treatments. We report a case of refractory cutaneous polyarteritis nodosa who failed three immunosuppressive therapies and three different biological agents. He was successfully treated with two rituximab 1000 mg infusions with a good efficacy and tolerance. This case demonstrates the safety and efficacy of rituximab in treatment of refractory cutaneous polyarteritis nodosa.

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