Emerging Infectious Diseases (Nov 2021)
Multinational Observational Cohort Study of COVID-19–Associated Pulmonary Aspergillosis
- Nico A.F. Janssen,
- Rémy Nyga,
- Lore Vanderbeke,
- Cato Jacobs,
- Mehmet Ergün,
- Jochem B. Buil,
- Karin van Dijk,
- Josje Altenburg,
- Catherine S.C. Bouman,
- Hans I. van der Spoel,
- Bart J.A. Rijnders,
- Albert Dunbar,
- Jeroen A. Schouten,
- Katrien Lagrou,
- Marc Bourgeois,
- Marijke Reynders,
- Niels van Regenmortel,
- Lynn Rutsaert,
- Piet Lormans,
- Simon Feys,
- Yves Debavaye,
- Fabienne Tamion,
- Damien Costa,
- Julien Maizel,
- Hervé Dupont,
- Taieb Chouaki,
- Saad Nseir,
- Boualem Sendid,
- Roger J.M. Brüggemann,
- Frank L. van de Veerdonk,
- Joost Wauters,
- Paul E. Verweij
Affiliations
- Nico A.F. Janssen
- Rémy Nyga
- Lore Vanderbeke
- Cato Jacobs
- Mehmet Ergün
- Jochem B. Buil
- Karin van Dijk
- Josje Altenburg
- Catherine S.C. Bouman
- Hans I. van der Spoel
- Bart J.A. Rijnders
- Albert Dunbar
- Jeroen A. Schouten
- Katrien Lagrou
- Marc Bourgeois
- Marijke Reynders
- Niels van Regenmortel
- Lynn Rutsaert
- Piet Lormans
- Simon Feys
- Yves Debavaye
- Fabienne Tamion
- Damien Costa
- Julien Maizel
- Hervé Dupont
- Taieb Chouaki
- Saad Nseir
- Boualem Sendid
- Roger J.M. Brüggemann
- Frank L. van de Veerdonk
- Joost Wauters
- Paul E. Verweij
- DOI
- https://doi.org/10.3201/eid2711.211174
- Journal volume & issue
-
Vol. 27,
no. 11
pp. 2892 – 2898
Abstract
We performed an observational study to investigate intensive care unit incidence, risk factors, and outcomes of coronavirus disease–associated pulmonary aspergillosis (CAPA). We found 10%–15% CAPA incidence among 823 patients in 2 cohorts. Several factors were independently associated with CAPA in 1 cohort and mortality rates were 43%–52%.
Keywords
- respiratory infections
- severe acute respiratory syndrome coronavirus 2
- SARS-CoV-2
- SARS
- COVID-19
- coronavirus disease
