Nature Communications (Oct 2018)

Hub-organized parallel circuits of central circadian pacemaker neurons for visual photoentrainment in Drosophila

  • Meng-Tong Li,
  • Li-Hui Cao,
  • Na Xiao,
  • Min Tang,
  • Bowen Deng,
  • Tian Yang,
  • Taishi Yoshii,
  • Dong-Gen Luo

DOI
https://doi.org/10.1038/s41467-018-06506-5
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 14

Abstract

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The central circadian clock in Drosophila is made up of ~ 150 anatomically distributed neurons; the circuits underlying photoentrainment is unclear. This study describes ex vivo patch-clamp recording of the eye-mediated light response of all known circadian clock neurons, and shows that they are organized in parallel circuits centered around a hub.