Viruses (Oct 2013)

CD8 and CD4 T Cells in West Nile Virus Immunity and Pathogenesis

  • Michael J. Bevan,
  • Jason Netland

DOI
https://doi.org/10.3390/v5102573
Journal volume & issue
Vol. 5, no. 10
pp. 2573 – 2584

Abstract

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CD4 and CD8 T lymphocytes are adaptive immune cells that play a key role in the immune response to pathogens. They have been extensively studied in a variety of model systems and the mechanisms by which they function are well described. However, the responses by these cell types vary widely from pathogen to pathogen. In this review, we will discuss the role of CD8 and CD4 T cells in the immune response to West Nile virus infection.

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