Nature Communications (Jun 2018)

Variability in the location of high frequency oscillations during prolonged intracranial EEG recordings

  • Stephen V. Gliske,
  • Zachary T. Irwin,
  • Cynthia Chestek,
  • Garnett L. Hegeman,
  • Benjamin Brinkmann,
  • Oren Sagher,
  • Hugh J. L. Garton,
  • Greg A. Worrell,
  • William C. Stacey

DOI
https://doi.org/10.1038/s41467-018-04549-2
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 14

Abstract

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High frequency oscillations (HFO) are a promising biomarker for identifying epileptogenic zones without the need to monitor spontaneous seizure episodes. Here the authors report that there is much variability in the location of HFOs offering a note of caution toward using HFO locations from short recordings as a guide for surgery.