Monitoring of vascular dysregulation in normotensive glaucoma

Abstract

Purpose: To study blood flow autoregulation in normotensive glaucoma using ultrasound dopplerography before and after a neuroprotectivetreatment.Methods: In the period of observation from 2010 to 2012, we examined 94 patients (183 eyes), of which 33 (61 eyes) — with normotensive glaucoma (NG), 31 (62 eyes) — with open-angle glaucoma (OAG) and 30 patients (60 eyes) was the control group. There were 40 men and women — 54. Mean age was 58.5±6.5 years.Results: Ultrasound dopplerography showed marked reduction of peak systolic, terminal diastolic velocity and an increase in resistance index CRA and SPCA (p <0.001) and OA (p <0.05) in the group of patients with NG compared to the norm.Conclusion: There is a certain tendency to improvement of hemodynamic parameters after treatment with neuroprotective that at the root does not negate the need for neuroprotection in NG.

Keywords

• normotensive glaucoma
• doppler sonography
• neuroprotection