Pericentral hydroxychloroquine retinopathy in a Caucasian female

Abstract

Purpose: To report a rare presentation of the pericentral pattern of hydroxychloroquine (HCQ) retinal toxicity in a Caucasian female. Observations: The patient presented with 20 years of exposure to HCQ, at a daily dose of 5.2mg/kg of actual body weight, and manifested a pericentral-only phenotype of HCQ toxicity, as demonstrated with detailed structural and functional testing. Conclusions and importance: Although rare, the pericentral pattern of HCQ toxicity may occur in Caucasian patients in the absence of paracentral changes.

Keywords

• Hydroxychloroquine
• Pericentral
• Toxicity
• Bull's eye maculopathy
• Plaquenil
• Multifocal electroretinogram