SURGICAL OUTCOME OF SUPRATENTORIAL GLIOMAS IN TERMS OF IMPROVEMENT IN SEIZURES DURING SIX MONTHS FOLLOW UP

Abstract

Naeem Ul Haq, Muhammad ishfaq Khattak, Bakht Zar khan, Zia Ur Rehman, Mumtaz Ali. Neurosurgery department medical teaching institution Govt lady reading hospital Peshawar ABSTRACT OBJECTIVE: To find out the surgical outcome of supratentorial gliomas in terms of improvement in seizures. METHODS: This prospective hospital-based study was conducted on patients with supratentorial gliomas, at Department of Neurosurgery, Lady Reading Hospital, Peshawar, from Dec 2011 to Nov 2013. Patients unfit for general anesthesia, not willing for surgery, infratentorial gliomas and other brain tumors were excluded from the study. Information about demographic details, clinical features, magnetic resonance imaging findings and histopathology report were recorded in a proforma. All the patients were followed postoperatively for 6 months for relief of seizures. RESULTS: Out of 100 patients with supratentorial gliomas, 56 were male. Their ages ranged from 10-80 years, with mean age of 45±5 years.Frontal lobe was involved in 40 cases and temporal lobe in 35 cases. In patients with gross total resection (n=55), the seizures control was reduced from 59% in first postoperative month to 37% until 6 months. In patients of subtotal resection (n=45), seizures control was reduced from 30% patients to 19% until 6 months follow-up, so total 56% patients had no seizures till 6 months of follow-up. After 6 months follow up 22 patients gained Engel class-I, 17 had class-IV and 11 patients had class-II and III Engel score. Seven (7%) patients had neuro-deficit and six (6%) patients expired within 6 months of follow up. CONCLUSION: The most common site for supratentorial gliomas is frontal lobe. Significant number of patients improved in terms of seizures control post-operatively. Mortality during six months was 6%. KEY WORDS: Surgical outcome (Non-MeSH), Glioma (MeSH), Seizures (MeSH).