Determination of the Binding Sites of Activators within the Proteasome Structure

Affiliations

Malgorzata Gizynska: Department of Biomedical Chemistry, Faculty of Chemistry, University of Gdansk, 80-308 Gdańsk, Poland
Julia Witkowska: Department of Biomedical Chemistry, Faculty of Chemistry, University of Gdansk, 80-308 Gdańsk, Poland
Przemyslaw Karpowicz: Department of Organic Chemistry, Faculty of Chemistry, University of Gdansk, 80-308 Gdańsk, Poland
Fabian Henneberg: Department for Structural Dynamics, Max-Planck Institute for Biophysical Chemistry, 37077 Göttingen
Ashwin Chari: Department for Structural Dynamics, Max-Planck Institute for Biophysical Chemistry, 37077 Göttingen
Artur Gieldon: Department of Theoretical Chemistry, Faculty of Chemistry, University of Gdansk, 80-308 Gdańsk, Poland
Elzbieta Jankowska: Department of Biomedical Chemistry, Faculty of Chemistry, University of Gdansk, 80-308 Gdańsk, Poland

Abstract

The proteasome degrade most of the proteins in eukaryotic cells, thereby controlling the keycellular processes [...]