Epilepsy and Hippocampal Injury

Abstract

The relationship between hippocampal cell loss and mossy fiber sprouting (MFS), and the occurrence of spontaneous seizures (epilepsy) following early-life status epilepticus was investigated in laboratory studies at the Division of Neurology, Children’s Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, PA.

Keywords

• hippocampal
• mossy fiber sprouting
• spontaneous seizures