Genistein and 17β-Estradiol Protect Hepatocytes from Fatty Degeneration by Mechanisms Involving Mitochondria, Inflammasome and Kinases Activation

• Serena Farruggio,
• Grazia Cocomazzi,
• Patrizia Marotta,
• Raffaele Romito,
• Daniela Surico,
• Giuseppe Calamita,
• Mattia Bellan,
• Mario Pirisi,
• Elena Grossini

Affiliations

Serena Farruggio

Laboratory of Physiology and Experimental Surgery, Department of Translational Medicine, Università del Piemonte Orientale, Novara, Italy; AGING Project, Department of Translational Medicine, Università del Piemonte Orientale, Novara, Italy

Grazia Cocomazzi

Laboratory of Physiology and Experimental Surgery, Department of Translational Medicine, Università del Piemonte Orientale, Novara, Italy; AGING Project, Department of Translational Medicine, Università del Piemonte Orientale, Novara, Italy

Patrizia Marotta

Laboratory of Physiology and Experimental Surgery, Department of Translational Medicine, Università del Piemonte Orientale, Novara, Italy; AGING Project, Department of Translational Medicine, Università del Piemonte Orientale, Novara, Italy

Raffaele Romito

General Surgery Unit, Maggiore della Carità University Hospital, Novara, Italy

Daniela Surico

AGING Project, Department of Translational Medicine, Università del Piemonte Orientale, Novara, Italy; Gynecology Division, Department of Translational Medicine, Università del Piemonte Orientale, Novara, Italy

Giuseppe Calamita

Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari “Aldo Moro”, Bari, Italy

Mattia Bellan

AGING Project, Department of Translational Medicine, Università del Piemonte Orientale, Novara, Italy; Internal Medicine Division, Department of Translational Medicine, Università del Piemonte Orientale, Novara, Italy

Mario Pirisi

AGING Project, Department of Translational Medicine, Università del Piemonte Orientale, Novara, Italy; Internal Medicine Division, Department of Translational Medicine, Università del Piemonte Orientale, Novara, Italy

Elena Grossini

Laboratory of Physiology and Experimental Surgery, Department of Translational Medicine, Università del Piemonte Orientale, Novara, Italy; AGING Project, Department of Translational Medicine, Università del Piemonte Orientale, Novara, Italy