Inhibition of Antiviral Innate Immunity by
<i>Avibirnavirus</i>
VP3 via Blocking TBK1-TRAF3 Complex Formation and IRF3 Activation

mSystems (Jun 2021)

Affiliations

Tingjuan Deng: MOA Key Laboratory of Animal Virology, Zhejiang University Center for Veterinary Sciences, Hangzhou, People’s Republic of China
Boli Hu: MOA Key Laboratory of Animal Virology, Zhejiang University Center for Veterinary Sciences, Hangzhou, People’s Republic of China
Xingbo Wang: MOA Key Laboratory of Animal Virology, Zhejiang University Center for Veterinary Sciences, Hangzhou, People’s Republic of China
Lulu Lin: MOA Key Laboratory of Animal Virology, Zhejiang University Center for Veterinary Sciences, Hangzhou, People’s Republic of China
Jianwei Zhou: MOA Key Laboratory of Animal Virology, Zhejiang University Center for Veterinary Sciences, Hangzhou, People’s Republic of China
Yuting Xu: MOA Key Laboratory of Animal Virology, Zhejiang University Center for Veterinary Sciences, Hangzhou, People’s Republic of China
Yan Yan: MOA Key Laboratory of Animal Virology, Zhejiang University Center for Veterinary Sciences, Hangzhou, People’s Republic of China
Xiaojuan Zheng: MOA Key Laboratory of Animal Virology, Zhejiang University Center for Veterinary Sciences, Hangzhou, People’s Republic of China
Jiyong Zhou: ORCiD; MOA Key Laboratory of Animal Virology, Zhejiang University Center for Veterinary Sciences, Hangzhou, People’s Republic of China

Abstract

Type I interferon plays a critical role in the host response against virus infection, including Avibirnavirus.