Frontiers in Neuroscience (Jun 2023)
An integrated full-head OPM-MEG system based on 128 zero-field sensors
- Orang Alem,
- Orang Alem,
- Orang Alem,
- K. Jeramy Hughes,
- K. Jeramy Hughes,
- K. Jeramy Hughes,
- Isabelle Buard,
- Teresa P. Cheung,
- Teresa P. Cheung,
- Teresa P. Cheung,
- Tyler Maydew,
- Andreas Griesshammer,
- Kendall Holloway,
- Aaron Park,
- Vanessa Lechuga,
- Collin Coolidge,
- Marja Gerginov,
- Erik Quigg,
- Alexander Seames,
- Eugene Kronberg,
- Peter Teale,
- Svenja Knappe,
- Svenja Knappe,
- Svenja Knappe
Affiliations
- Orang Alem
- FieldLine Medical, Boulder, CO, United States
- Orang Alem
- Paul M. Rady Department of Mechanical Engineering, University of Colorado Boulder, Boulder, CO, United States
- Orang Alem
- FieldLine Industries, Boulder, CO, United States
- K. Jeramy Hughes
- FieldLine Medical, Boulder, CO, United States
- K. Jeramy Hughes
- Paul M. Rady Department of Mechanical Engineering, University of Colorado Boulder, Boulder, CO, United States
- K. Jeramy Hughes
- FieldLine Industries, Boulder, CO, United States
- Isabelle Buard
- Anschutz Medical Campus, University of Colorado Denver, Denver, CO, United States
- Teresa P. Cheung
- FieldLine Medical, Boulder, CO, United States
- Teresa P. Cheung
- School of Engineering, Simon Fraser University, Burnaby, BC, Canada
- Teresa P. Cheung
- Surrey Memorial Hospital, Fraser Health Authority, Surrey, BC, Canada
- Tyler Maydew
- FieldLine Medical, Boulder, CO, United States
- Andreas Griesshammer
- FieldLine Medical, Boulder, CO, United States
- Kendall Holloway
- FieldLine Medical, Boulder, CO, United States
- Aaron Park
- FieldLine Medical, Boulder, CO, United States
- Vanessa Lechuga
- FieldLine Medical, Boulder, CO, United States
- Collin Coolidge
- FieldLine Medical, Boulder, CO, United States
- Marja Gerginov
- Paul M. Rady Department of Mechanical Engineering, University of Colorado Boulder, Boulder, CO, United States
- Erik Quigg
- Paul M. Rady Department of Mechanical Engineering, University of Colorado Boulder, Boulder, CO, United States
- Alexander Seames
- Anschutz Medical Campus, University of Colorado Denver, Denver, CO, United States
- Eugene Kronberg
- Anschutz Medical Campus, University of Colorado Denver, Denver, CO, United States
- Peter Teale
- Anschutz Medical Campus, University of Colorado Denver, Denver, CO, United States
- Svenja Knappe
- FieldLine Medical, Boulder, CO, United States
- Svenja Knappe
- Paul M. Rady Department of Mechanical Engineering, University of Colorado Boulder, Boulder, CO, United States
- Svenja Knappe
- FieldLine Industries, Boulder, CO, United States
- DOI
- https://doi.org/10.3389/fnins.2023.1190310
- Journal volume & issue
-
Vol. 17
Abstract
Compact optically-pumped magnetometers (OPMs) are now commercially available with noise floors reaching 10 fT/Hz1/2. However, to be used effectively for magnetoencephalography (MEG), dense arrays of these sensors are required to operate as an integrated turn-key system. In this study, we present the HEDscan, a 128-sensor OPM MEG system by FieldLine Medical, and evaluate its sensor performance with regard to bandwidth, linearity, and crosstalk. We report results from cross-validation studies with conventional cryogenic MEG, the Magnes 3,600 WH Biomagnetometer by 4-D Neuroimaging. Our results show high signal amplitudes captured by the OPM-MEG system during a standard auditory paradigm, where short tones at 1000 Hz were presented to the left ear of six healthy adult volunteers. We validate these findings through an event-related beamformer analysis, which is in line with existing literature results.
Keywords
- optically-pumped magnetometer
- HEDscan
- magnetoencephalography
- system integration
- cross-validation
- OPM
