Patient Centric Pharmaceutical Drug Product Design—The Impact on Medication Adherence
Enrica Menditto,
Valentina Orlando,
Giuseppe De Rosa,
Paola Minghetti,
Umberto Maria Musazzi,
Caitriona Cahir,
Marta Kurczewska-Michalak,
Przemysław Kardas,
Elísio Costa,
José Manuel Sousa Lobo,
Isabel F Almeida
Affiliations
Enrica Menditto
CIRFF, Centre of Pharmacoeconomics, Department of Pharmacy, University of Naples Federico II, Corso Umberto I, 40, 80138 Napoli NA, Italy
Valentina Orlando
CIRFF, Centre of Pharmacoeconomics, Department of Pharmacy, University of Naples Federico II, Corso Umberto I, 40, 80138 Napoli NA, Italy
Giuseppe De Rosa
Department of Pharmacy, University of Naples Federico II Corso Umberto I, 40, 80138 Napoli NA, Italy
Paola Minghetti
Department of Pharmaceutical Sciences, Università degli Studi di Milano, Via G. Colombo 71, 20133 Milan, Italy
Umberto Maria Musazzi
Department of Pharmaceutical Sciences, Università degli Studi di Milano, Via G. Colombo 71, 20133 Milan, Italy
Caitriona Cahir
Division of Population Health Sciences, Royal College of Surgeons, Beaux Lane House, Mercer Street, Dublin 2, Ireland
Marta Kurczewska-Michalak
Department of Family Medicine, Medical University of Lodz, 60, Narutowicza St., 90-136 Lodz, Poland
Przemysław Kardas
Department of Family Medicine, Medical University of Lodz, 60, Narutowicza St., 90-136 Lodz, Poland
Elísio Costa
UCIBIO/REQUIMTE, Faculty of Pharmacy and Porto4Ageing, University of Porto, Rua Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal
José Manuel Sousa Lobo
UCIBIO/REQUIMTE, MedTech-Laboratory of Pharmaceutical Technology, Department of Drug Sciences, Faculty of Pharmacy, University of Porto, Rua Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal
Isabel F Almeida
UCIBIO/REQUIMTE, MedTech-Laboratory of Pharmaceutical Technology, Department of Drug Sciences, Faculty of Pharmacy, University of Porto, Rua Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal
Medication adherence is a growing concern for public health and poor adherence to therapy has been associated with poor health outcomes and higher costs for patients. Interventions for improving adherence need to consider the characteristics of the individual therapeutic regimens according to the needs of the patients. In particular, geriatric and paediatric populations as well as dermatological patients have special needs/preferences that should be considered when designing drug products. Patient Centric Drug Product Pharmaceutical Design (PCDPD) offers the opportunity to meet the needs and preferences of patients. Packaging, orodispersible formulations, fixed dose combinations products, multiparticulate formulations, topical formulations and 3D printing are of particular relevance in a PCDPD process. These will be addressed in this review as well as their impact on medication adherence.
