Safety and efficiency of therapy by gene-engineering-biological preparations of rheumatoid arthritis

Abstract

In this review of the literature, questions of the efficacy and safety of therapy with genetically engineered biological preparations for rheumatoid arthritis are discussed. The results of randomized trials of recent years are described in detail. Systematic literature search was conducted on the databases Scopus, Web of Science, MedLine, elibrary and others.

Keywords

• genetically engineered biological preparations
• rheumatoid arthritis
• tocilizumab
• rituximab
• infliximab
• etanercept