Nature Communications (Jul 2020)

Collective cell mechanics of epithelial shells with organoid-like morphologies

  • Jan Rozman,
  • Matej Krajnc,
  • Primož Ziherl

DOI
https://doi.org/10.1038/s41467-020-17535-4
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 9

Abstract

Read online

The physical origins of man-made tissue morphologies with organ-like microscopic anatomy and functionality remain poorly understood. Here, authors propose a mechanistic theory of these structures, employing a 3D vertex model to reproduce the characteristic morphologies such as branched shapes.