Nature Communications (Feb 2018)
Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging
- Gabriel Oh,
- Sasha Ebrahimi,
- Matthew Carlucci,
- Aiping Zhang,
- Akhil Nair,
- Daniel E. Groot,
- Viviane Labrie,
- Peixin Jia,
- Edward S. Oh,
- Richie H. Jeremian,
- Miki Susic,
- Tenjin C. Shrestha,
- Martin R. Ralph,
- Juozas Gordevičius,
- Karolis Koncevičius,
- Art Petronis
Affiliations
- Gabriel Oh
- The Krembil Family Epigenetics Laboratory, The Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health
- Sasha Ebrahimi
- The Krembil Family Epigenetics Laboratory, The Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health
- Matthew Carlucci
- The Krembil Family Epigenetics Laboratory, The Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health
- Aiping Zhang
- The Krembil Family Epigenetics Laboratory, The Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health
- Akhil Nair
- The Krembil Family Epigenetics Laboratory, The Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health
- Daniel E. Groot
- The Krembil Family Epigenetics Laboratory, The Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health
- Viviane Labrie
- The Krembil Family Epigenetics Laboratory, The Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health
- Peixin Jia
- The Krembil Family Epigenetics Laboratory, The Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health
- Edward S. Oh
- The Krembil Family Epigenetics Laboratory, The Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health
- Richie H. Jeremian
- The Krembil Family Epigenetics Laboratory, The Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health
- Miki Susic
- The Krembil Family Epigenetics Laboratory, The Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health
- Tenjin C. Shrestha
- Department of Cell and Systems Biology, University of Toronto
- Martin R. Ralph
- Department of Psychology, University of Toronto
- Juozas Gordevičius
- Institute of Biotechnology, Life Sciences Center, Vilnius University
- Karolis Koncevičius
- Institute of Biotechnology, Life Sciences Center, Vilnius University
- Art Petronis
- The Krembil Family Epigenetics Laboratory, The Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health
- DOI
- https://doi.org/10.1038/s41467-018-03073-7
- Journal volume & issue
-
Vol. 9,
no. 1
pp. 1 – 11
Abstract
While epigenetic factors have been implicated in the circadian rhythm, the detection of circadian cytosine modifications has remained elusive. Here the authors identify a large number of epigenetically variable cytosines that show circadian oscillations in their modification status in mice.
